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1991 1
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2000 1
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2003 4
2004 12
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2007 21
2008 19
2009 28
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962 results

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Page 1
Ferritin nanoparticle-based SpyTag/SpyCatcher-enabled click vaccine for tumor immunotherapy.
Wang W, Liu Z, Zhou X, Guo Z, Zhang J, Zhu P, Yao S, Zhu M. Wang W, et al. Nanomedicine. 2019 Feb;16:69-78. doi: 10.1016/j.nano.2018.11.009. Epub 2018 Dec 8. Nanomedicine. 2019. PMID: 30529790
These ferritin nanoparticles are rapidly drained to lymph nodes and target dendritic cells, especially CD8alpha(+) population, upon subcutaneous immunization. ...The anti-tumor effect was further enhanced in combination with PD-1 checkpoint blockade. Together, our s …
These ferritin nanoparticles are rapidly drained to lymph nodes and target dendritic cells, especially CD8alpha(+) population, …
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates.
Weidenbacher PA, Sanyal M, Friedland N, Tang S, Arunachalam PS, Hu M, Kumru OS, Morris MK, Fontenot J, Shirreff L, Do J, Cheng YC, Vasudevan G, Feinberg MB, Villinger FJ, Hanson C, Joshi SB, Volkin DB, Pulendran B, Kim PS. Weidenbacher PA, et al. Nat Commun. 2023 Apr 17;14(1):2149. doi: 10.1038/s41467-023-37417-9. Nat Commun. 2023. PMID: 37069151 Free PMC article.
While the rapid development of COVID-19 vaccines has been a scientific triumph, the need remains for a globally available vaccine that provides longer-lasting immunity against present and future SARS-CoV-2 variants of concern (VOCs). Here, we describe DCFHP, a ferritin-bas …
While the rapid development of COVID-19 vaccines has been a scientific triumph, the need remains for a globally available vaccine that provi …
Ferritin: A Multifunctional Nanoplatform for Biological Detection, Imaging Diagnosis, and Drug Delivery.
Song N, Zhang J, Zhai J, Hong J, Yuan C, Liang M. Song N, et al. Acc Chem Res. 2021 Sep 7;54(17):3313-3325. doi: 10.1021/acs.accounts.1c00267. Epub 2021 Aug 20. Acc Chem Res. 2021. PMID: 34415728 Review.
Ferritins are spherical iron storage proteins within cells that are composed of a combination of 24 subunits of two types, heavy-chain ferritin (HFn) and light-chain ferritin (LFn). ...We finally discuss the prospect of ferritin-based formulations to b …
Ferritins are spherical iron storage proteins within cells that are composed of a combination of 24 subunits of two types, heavy-chai …
Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses.
Ma X, Zou F, Yu F, Li R, Yuan Y, Zhang Y, Zhang X, Deng J, Chen T, Song Z, Qiao Y, Zhan Y, Liu J, Zhang J, Zhang X, Peng Z, Li Y, Lin Y, Liang L, Wang G, Chen Y, Chen Q, Pan T, He X, Zhang H. Ma X, et al. Immunity. 2020 Dec 15;53(6):1315-1330.e9. doi: 10.1016/j.immuni.2020.11.015. Epub 2020 Nov 25. Immunity. 2020. PMID: 33275896 Free PMC article.
RBD and RBD-HR nanoparticle vaccinated hACE2 transgenic mice vaccinated with RBD and/or RBD-HR nanoparticles exhibited reduced viral load in the lungs after SARS-CoV-2 challenge. ...RBD- and HR-based nanoparticles thus present a promising vaccination approach …
RBD and RBD-HR nanoparticle vaccinated hACE2 transgenic mice vaccinated with RBD and/or RBD-HR nanoparticles exhibited reduced …
Silver nanoparticle synthesis in human ferritin by photochemical reduction.
Moglia I, Santiago M, Soler M, Olivera-Nappa A. Moglia I, et al. J Inorg Biochem. 2020 May;206:111016. doi: 10.1016/j.jinorgbio.2020.111016. Epub 2020 Feb 1. J Inorg Biochem. 2020. PMID: 32142941
Potential biomedical applications of ferritin-nanoparticle complex will require the use of human ferritin to provide a safer and low-risk alternative for the delivery of metallic nanoparticles into the body. ...Additionally, we report important paramet …
Potential biomedical applications of ferritin-nanoparticle complex will require the use of human ferritin to provide a …
Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies.
Kanekiyo M, Wei CJ, Yassine HM, McTamney PM, Boyington JC, Whittle JR, Rao SS, Kong WP, Wang L, Nabel GJ. Kanekiyo M, et al. Nature. 2013 Jul 4;499(7456):102-6. doi: 10.1038/nature12202. Epub 2013 May 22. Nature. 2013. PMID: 23698367 Free PMC article.
Here we use knowledge of protein structure to design self-assembling nanoparticles that elicit broader and more potent immunity than traditional influenza vaccines. The viral haemagglutinin was genetically fused to ferritin, a protein that naturally forms nanopar …
Here we use knowledge of protein structure to design self-assembling nanoparticles that elicit broader and more potent immunity than …
Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques.
Yu J, Thomas PV, Sciacca M, Wu C, Liu J, He X, Miller J, Hachmann NP, Surve N, McMahan K, Jacob-Dolan C, Powers O, Hall K, Barrett J, Hope D, Mazurek CR, Murdza T, Chang WC, Golub E, Rees PA, Peterson CE, Hajduczki A, Chen WH, Martinez EJ, Hussin E, Lange C, Gong H, Matyas GR, Rao M, Suthar M, Boursiquot M, Cook A, Pessaint L, Lewis MG, Andersen H, Bolton DL, Michael NL, Joyce MG, Modjarrad K, Barouch DH. Yu J, et al. Cell Rep Med. 2023 Apr 18;4(4):101018. doi: 10.1016/j.xcrm.2023.101018. Epub 2023 Mar 27. Cell Rep Med. 2023. PMID: 37023746 Free PMC article.
We report the immunogenicity and protective efficacy of vaccine regimens consisting of the vector-based Ad26.COV2.S vaccine and the adjuvanted spike ferritin nanoparticle (SpFN) vaccine against a high-dose, mismatched Omicron BA.5 challenge in macaques. ...
We report the immunogenicity and protective efficacy of vaccine regimens consisting of the vector-based Ad26.COV2.S vaccine and the adjuvant …
Engineered Ferritin Nanoparticle Vaccines Enable Rapid Screening of Antibody Functionalization to Boost Immune Responses.
Vu MN, Pilkington EH, Lee WS, Tan HX, Davis TP, Truong NP, Kent SJ, Wheatley AK. Vu MN, et al. Adv Healthc Mater. 2023 Jul;12(17):e2202595. doi: 10.1002/adhm.202202595. Epub 2023 Feb 24. Adv Healthc Mater. 2023. PMID: 36786027
However, studying the effects of different targeting antibodies head-to-head is challenging due to the lack of a feasible method that allows rapid screening of multiple antibodies for their impact on immunogenicity. Here self-assembling ferritin nanoparticles are pr …
However, studying the effects of different targeting antibodies head-to-head is challenging due to the lack of a feasible method that allows …
A ferritin nanoparticle vaccine for foot-and-mouth disease virus elicited partial protection in mice.
Chen Y, Hu Y, Chen H, Li X, Qian P. Chen Y, et al. Vaccine. 2020 Jul 31;38(35):5647-5652. doi: 10.1016/j.vaccine.2020.06.063. Epub 2020 Jul 3. Vaccine. 2020. PMID: 32624251
We used a baculovirus expression system to express four recombinant proteins (VP1, VP1-Ft, G-H loop-Ft, and ferritin) and the protective immunity of the FMD ferritin nanoparticle vaccines was evaluated in mice. ...The G-H loop-Ft vaccine provided a 77.8% surv …
We used a baculovirus expression system to express four recombinant proteins (VP1, VP1-Ft, G-H loop-Ft, and ferritin) and the protect …
R848 Adjuvant Laden With Self-Assembled Nanoparticle-Based mRNA Vaccine Elicits Protective Immunity Against H5N1 in Mice.
Zhuang X, Chen L, Yang S, Xia S, Xu Z, Zhang T, Zeng B, Yu T, Yu N, Wang W, Lu H, Tian M, Jin N. Zhuang X, et al. Front Immunol. 2022 May 31;13:836274. doi: 10.3389/fimmu.2022.836274. eCollection 2022. Front Immunol. 2022. PMID: 35711431 Free PMC article.
We prepared cationic lipid nanoparticles for mRNA delivery, named LNP-Man (mannose-modified lipid nanoparticles). Cell transfection results showed that Flu-Fe/CD5-Flu-Fe containing ferritin could express the target antigens HA2 and M2e more efficiently than F …
We prepared cationic lipid nanoparticles for mRNA delivery, named LNP-Man (mannose-modified lipid nanoparticles). Cell transfe …
962 results

Searches related to "ferritin nanoparticle"